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PD-1 and PD-L1 correlated gene expression profiles and their association with clinical outcomes of breast cancer

9 Sept 2019

Abstract excerpt

BACKGROUND: Immunotherapies that targeting programmed cell death 1 (PD-1) and programmed death-ligand 1 (PD-L1) have obtained prominent success in breast cancer (BC). However, not all the patients benefit from the antibody therapy. This study aimed to identify PD-1/PD-L1 correlated genes and pathways as well as investigate their potential as prognostic marker in BC. MATERIALS AND METHODS: By analysing...

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PMID: 31516390
DOI: 10.1186/s12935-019-0955-2

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