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Article

Next-generation Sequencing as a Potential Diagnostic Adjunct in Distinguishing Between Desmoplastic Melanocytic Neoplasms.

The American journal of surgical pathology - 1 Mar 2023

Roth Andrew, Boutko Anastasiya, Lampley Nathaniel, Dhillon Soneet, Hagstrom Michael, Olivares Shantel, Dittman David, Jennings Lawrence, Santana Dos Santos Lucas, Busam Klaus, Gerami Pedram

Abstract excerpt

Desmoplastic melanomas (DMs) are often challenging to diagnose and ancillary tests, such as immunohistochemistry, have limitations. One challenge is distinguishing DM from benign desmoplastic melanocytic neoplasms. In this study, we explored the utility of next-generation sequencing data in the diagnosis of DMs versus desmoplastic Spitz nevi (DSN) and desmoplastic nevi (DN). We sequenced 47 cases and retrieved 12...

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Share to Cancer Genomics and Diagnostics
Share to Cutaneous Melanoma Detection and Management

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to High-Throughput Nucleotide Sequencing

Share to Melanoma

Share to Melanoma and MAPK Pathways

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Share to Nevus, Pigmented

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Source

Identifiers

PMID: 36383901
DOI: 10.1097/PAS.0000000000001999

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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