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Article

Krüppel-like Factor 13 Promotes HCC Progression by Transcriptional Regulation of HMGCS1-mediated Cholesterol Synthesis

7 Mar 2022

Abstract excerpt

Background and Aims: Krüppel-like factor (KLF) has a role in the occurrence, development and metabolism of cancer. We aimed to explore the role and potential molecular mechanism of KLF13 in the growth and migration of liver cancer cells. Methods: function of KLF13 in HCC cells. The effect of KLF13 on xenograft tumor growth in vivo was evaluated. The cholesterol content of HCC cells was determined by an indicator...

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PMID: 36381108
DOI: 10.14218/jcth.2021.00370

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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