Article
Single-cell RNA sequencing highlights the functional role of human endogenous retroviruses in gallbladder cancer
29 Oct 2022
Abstract excerpt
BACKGROUND: Gallbladder cancer (GBC), the most common malignancy of the biliary tract, shows late diagnosis and low survival rate and requires continued search for new diagnostic biomarkers and therapeutic targets. Human endogenous retroviruses (HERVs) are specifically prone to be reactivated in diverse cancers and are implicated in cancer progression and immunotherapy. METHODS: Single-cell RNA sequencing was...
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