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Article

Divergent viral presentation among human tumors and adjacent normal tissues.

Scientific reports - 24 Jun 2016

Cao Song, Wendl Michael C, Wyczalkowski Matthew A, Wylie Kristine, Ye Kai, Jayasinghe Reyka, Xie Mingchao, Wu Song, Niu Beifang, Grubb Robert, Johnson Kimberly J, Gay Hiram, Chen Ken, Rader Janet S, Dipersio John F, Chen Feng, Ding Li

Abstract excerpt

We applied a newly developed bioinformatics system called VirusScan to investigate the viral basis of 6,813 human tumors and 559 adjacent normal samples across 23 cancer types and identified 505 virus positive samples with distinctive, organ system- and cancer type-specific distributions. We found that herpes viruses (e.g., subtypes HHV4, HHV5, and HHV6) that are highly prevalent across cancers of the digestive...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 27339696
DOI: 10.1038/srep28294
PMCID: PMC4919655

Genes

PTPN13

Provenance

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