Article
Canine Coronavirus Activates Aryl Hydrocarbon Receptor during In Vitro Infection.
Viruses - 3 Nov 2022
Cerracchio Claudia, Serra Francesco, Amoroso Maria Grazia, Fiorito Filomena
Abstract excerpt
The aryl hydrocarbon receptor (AhR) is a ligand-activated transcription factor that interacts with substrates, including microbial metabolites. Recent advances reveal that AhR is involved in the host response to coronaviruses (CoVs) infection. Particularly, AhR antagonists decrease the expression of angiotensin-converting enzyme 2 (ACE2) via AhR up-regulation, resulting in suppression of severe acute respiratory...
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