Article
Insights into Genomic Dynamics and Plasticity in the Monkeypox Virus from the 2022 Outbreak.
International journal of molecular sciences - 29 Jan 2026
Deiana Michela, Locatelli Elena, Veschetti Laura, Malagò Simone, Mori Antonio, Lavezzari Denise, Accordini Silvia, Ronzoni Niccolò, Angheben Andrea, Malerba Giovanni, Tacconelli Evelina, Cusi Maria Grazia, Gobbi Federico Giovanni, Piubelli Chiara, Castilletti Concetta
Abstract excerpt
The 2022 global mpox outbreak represented a turning point in the Monkeypox virus (MPXV) epidemiology, highlighting the incredible capability of this virus to adapt to different conditions, also in a non-endemic context. To investigate the genomic dynamics of MPXV 2022 strains, we performed whole-genome sequencing of 40 clinical samples from 16 Italian patients across multiple anatomical sites and timepoints...
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