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Simulated Microgravity Modulates Focal Adhesion Gene Expression in Human Neural Stem Progenitor Cells

9 Nov 2022

Abstract excerpt

We analyzed the morphology and the transcriptomic changes of human neural stem progenitor cells (hNSPCs) grown on laminin in adherent culture conditions and subjected to simulated microgravity for different times in a random positioning machine apparatus. Low-cell-density cultures exposed to simulated microgravity for 24 h showed cell aggregate formation and significant modulation of several genes involved in...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36362982
DOI: 10.3390/life12111827

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