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Cryptogenetic liver cirrhosis and prothrombotic mutations - A mere association?

Revista espanola de enfermedades digestivas - 1 Sept 2016

Monereo Muñoz María, Aguilera García Selena Gala, de la Barreda Heusser Raquel, González Arnay Emilio, García Hernández Sonia, González Reimers Emilio

Abstract excerpt

Thrombin activation and microthrombosis of intrahepatic portal venules is a common feature in liver cirrhosis, due in part to relative protein C deficiency and altered coagulation-anticoagulation-fibrinolysis balance. Extension of this microthrombotic process to larger portal vessels explains the increased incidence of portal vein thrombosis in liver cirrhosis. Thrombin not only leads to thrombosis, but also...

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PMID: 26785615
DOI: 10.17235/reed.2016.3871/2015

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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