Article

Novel Immunoglobulin Domain Proteins Provide Insights into Evolution and Pathogenesis Mechanisms of SARS-Related Coronaviruses

2020-03-07

Abstract excerpt

<h4>ABSTRACT</h4> A novel coronavirus (SARS-CoV-2) is the causative agent of an emergent severe respiratory disease (COVID-19) in humans that is threatening to result in a global health crisis. By using genomic, sequence, structural and evolutionary analysis, we show that Alpha- and Beta-CoVs possess several novel families of immunoglobulin (Ig) domain proteins, including ORF8 and ORF7a from SARS-related coronavi...

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Literature Corpus work: 47bbdf8f-cb85-5929-8f3d-2af25d2cddfa
DOI: 10.1101/2020.03.04.977736

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