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Article

NF2 mutations are associated with resistance to radiation therapy for grade 2 and grade 3 recurrent meningiomas.

Journal of neuro-oncology - 1 Jan 2023

Vasan Vikram, Dullea Jonathan T, Devarajan Alex, Ali Muhammad, Rutland John W, Gill Corey M, Kinoshita Yayoi, McBride Russell B, Gliedman Paul, Bederson Joshua, Donovan Michael, Sebra Robert, Umphlett Melissa, Shrivastava Raj K

Abstract excerpt

PURPOSE: High grade meningiomas have a prognosis characterized by elevated recurrence rates and radiation resistance. Recent work has highlighted the importance of genomics in meningioma prognostication. This study aimed to assess the relationship between the most common meningioma genomic alteration (NF2) and response to postoperative radiation therapy (RT). METHODS: From an institutional tissue bank, grade 2...

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Identifiers

PMID: 36436149
DOI: 10.1007/s11060-022-04197-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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