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Article

D3EGFR: a webserver for deep learning-guided drug sensitivity prediction and drug response information retrieval for EGFR mutation-driven lung cancer.

Briefings in bioinformatics - 27 Mar 2024

Shi Yulong, Li Chongwu, Zhang Xinben, Peng Cheng, Sun Peng, Zhang Qian, Wu Leilei, Ding Ying, Xie Dong, Xu Zhijian, Zhu Weiliang

Abstract excerpt

As key oncogenic drivers in non-small-cell lung cancer (NSCLC), various mutations in the epidermal growth factor receptor (EGFR) with variable drug sensitivities have been a major obstacle for precision medicine. To achieve clinical-level drug recommendations, a platform for clinical patient case retrieval and reliable drug sensitivity prediction is highly expected. Therefore, we built a database, D3EGFRdb, with...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38555474
DOI: 10.1093/bib/bbae121
PMCID: PMC10981678

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EGFR

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