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HLA-A, -B, -C, -DPB1, -DQB1 and -DRB1 allele frequencies of North Tanzanian Maasai.

Human immunology - 1 Feb 2023

Barton Amber, Ramadhani Athumani, Mafuru Elias, Mtuy Tara, Massae Patrick, Malissa Aiweda, Derrick Tamsyn, Houghton Joanna, Harte Anna, Payne Thomas, Pickering Harry, Burton Matthew J, Roberts Chrissy H, Holland Martin J

Abstract excerpt

Locus-specific amplicon sequencing was used to HLA type 336 participants of Maasai ethnicity at the HLA-A, -B, -C, -DRB1, -DQB1 and -DPB1 loci. Participants were recruited from three study villages in North Tanzania, for the purpose of investigating risk factors for trachomatous scarring in children. Other than HLA-A, all loci significantly deviated from Hardy-Weinberg equilibrium, possibly due to high...

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PMID: 36335052
DOI: 10.1016/j.humimm.2022.10.008

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