Article
Three-dimensional cell culture: from evolution to revolution
21 May 2018
Abstract excerpt
Recent advances in the isolation of tissue-resident adult stem cells and the identification of inductive factors that efficiently direct differentiation of human pluripotent stem cells along specific lineages have facilitated the development of high-fidelity modelling of several tissues in vitro . Many of the novel approaches have employed self-organizing three-dimensional (3D) culturing of organoids, which offer...
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