Article
The polymorphisms of MSH6 gene are associated with AIDS progression in a northern Chinese population.
Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2016
Wang Chuntao, Zhao Chunyan, Zhang Xuelong, Xu Lidan, Jia Xueyuan, Sun Haiming, Yu Jingcui, Zhang Guangfa, He Ning, Li Qiuyan, Qiao Yuandong, Fu Songbin
Abstract excerpt
It has been reported that DNA repair genes play an important role in HIV-1 infection and AIDS progression. One DNA repair pathway, the mismatch repair (MMR) is associated with a wide variety of tumors. However, the role of single nucleotide polymorphisms (SNPs) in the MMR genes and their importance in HIV-1 infection and AIDS progression remain unclear. In the present study, 479 HIV-1-infected and 487 healthy...
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