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Article

Complement Factor D as a Strategic Target for Regulating the Alternative Complement Pathway

9 Sept 2021

Abstract excerpt

The complement system is central to first-line defense against invading pathogens. However, excessive complement activation and/or the loss of complement regulation contributes to the development of autoimmune diseases, systemic inflammation, and thrombosis. One of the three pathways of the complement system, the alternative complement pathway, plays a vital role in amplifying complement activation and pathway...

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Share to Blood Coagulation and Thrombosis Mechanisms
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Identifiers

PMID: 34566967
DOI: 10.3389/fimmu.2021.712572

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