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Article

Stability and expression of SARS-CoV-2 spike-protein mutations.

Molecular and cellular biochemistry - 1 Jun 2023

Bæk Kristoffer T, Mehra Rukmankesh, Kepp Kasper P

Abstract excerpt

Protein fold stability likely plays a role in SARS-CoV-2 S-protein evolution, together with ACE2 binding and antibody evasion. While few thermodynamic stability data are available for S-protein mutants, many systematic experimental data exist for their expression. In this paper, we explore whether such expression levels relate to the thermodynamic stability of the mutants. We studied mutation-induced SARS-CoV-2...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 36302994
DOI: 10.1007/s11010-022-04588-w
PMCID: PMC9612610

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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