Article
Exploring the association between brain-derived neurotrophic factor levels and longitudinal psychopathological and cognitive changes in Sardinian psychotic patients.
European psychiatry : the journal of the Association of European Psychiatrists - 25 Oct 2022
Isayeva Ulker, Manchia Mirko, Collu Roberto, Primavera Diego, Deriu Luca, Caboni Edoardo, Iaselli Novella, Sundas Davide, Tusconi Massimo, Pinna Federica, Paribello Pasquale, Scherma Maria, Pisanu Claudia, Meloni Anna, Zai Clement C, Congiu Donatella, Squassina Alessio, Fratta Walter, Fadda Paola, Carpiniello Bernardo
Abstract excerpt
BACKGROUND AND HYPOTHESIS: Schizophrenia spectrum disorders are among the most debilitating mental disorders and has complex pathophysiological underpinnings. There is growing evidence that brain-derived neurotrophic factor (BDNF) can play a role in its pathogenesis. The present study investigated the longitudinal variation of serum BDNF levels in a 24-month observational prospective cohort study of Sardinian...
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