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Article

Genetic polymorphisms of BDNF on cognitive functions in drug-naive first episode patients with schizophrenia.

Scientific reports - 8 Oct 2021

Su Xiuru, Qiao Limin, Liu Qing, Shang Yujie, Guan Xiaoni, Xiu Meihong, Zhang Xiangyang

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) is reported to be involved in cognitive decline in patients with schizophrenia (SZ). Previous studies have found that cognitive deficits remain stable during the chronic disease phase in SZ, but the findings were inconsistent. The role of BDNF in cognitive deficits at different stage of illness remains unclear. This study aimed to examine the effect of BDNF polymorphisms...

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Identifiers

PMID: 34625629
DOI: 10.1038/s41598-021-99510-7
PMCID: PMC8501135

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