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Article

Circulating Proteins Influencing Psychiatric Disease: A Mendelian Randomization Study.

Biological psychiatry - 1 Jan 2023

Lu Tianyuan, Forgetta Vincenzo, Greenwood Celia M T, Zhou Sirui, Richards J Brent

Abstract excerpt

BACKGROUND: There is a pressing need for novel drug targets for psychiatric disorders. Circulating proteins are potential candidates because they are relatively easy to measure and modulate and play important roles in signaling. METHODS: We performed two-sample Mendelian randomization analyses to estimate the associations between circulating protein abundances and risk of 10 psychiatric disorders. Genetic...

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PMID: 36280454
DOI: 10.1016/j.biopsych.2022.08.015

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