Article
GPNMB promotes abdominal fat deposition in chickens: genetic variation, expressional profile, biological function, and transcriptional regulation.
Poultry science - 1 Dec 2022
Wang Dandan, Teng Menglin, Wang Yangyang, Cao Yuzhu, Tian Weihua, Wang Zhang, Guo Yulong, Li Hong, Li Zhuanjian, Jiang Ruirui, Li Guoxi, Tian Yadong, Liu Xiaojun
Abstract excerpt
Glycoprotein nonmetastatic melanoma protein B (GPNMB) is a vital secreted factor that promotes the occurrence of obesity in mammals. However, the effects of GPNMB on abdominal fat deposition is still unknown in chickens. In this study, we looked into the genetic and expression association of GPNMB gene with abdominal fat traits in chicken, and found that a genetic variation rs31126482 in GPNMB promoter was...
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