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Article

Integrative 3D genomics with multi-omics analysis and functional validation of genetic regulatory mechanisms of abdominal fat deposition in chickens.

Nature communications - 28 Oct 2024

Shen Linyong, Bai Xue, Zhao Liru, Zhou Jiamei, Chang Cheng, Li Xinquan, Cao Zhiping, Li Yumao, Luan Peng, Li Hui, Zhang Hui

Abstract excerpt

Chickens are the most abundant agricultural animals globally, with controlling abdominal fat deposition being a key objective in poultry breeding. While GWAS can identify genetic variants associated with abdominal fat deposition, the precise roles and mechanisms of these variants remain largely unclear. Here, we use male chickens from two lines divergently selected for abdominal fat deposition as experimental...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 39468045
DOI: 10.1038/s41467-024-53692-6
PMCID: PMC11519623

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