Article
Identification of a miRSNP Regulatory Axis in Abdominal Aortic Aneurysm by a Network and Pathway-Based Integrative Analysis.
Oxidative medicine and cellular longevity - 1 Jan 2022
Liu Shenrong, Liao Yanfen, Liu Changsong, Zhou Haobin, Chen Gui, Lu Weiling, Huang Zheng
Abstract excerpt
Abdominal aortic aneurysm (AAA) refers to local abnormal expansion of the abdominal aorta and mostly occurs in elderly men. MicroRNA (miRNA) is single-stranded RNA consisting of 18-25 nucleotides. It plays a key role in posttranscriptional gene expression and in the regulation of human functions and disease development. miRNA exerts its function mainly through the binding of complementary base pairs to the 3'...
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