Article
Identification of microRNAs associated with abdominal aortic aneurysms and peripheral arterial disease.
The British journal of surgery - 1 Jun 2015
Stather P W, Sylvius N, Sidloff D A, Dattani N, Verissimo A, Wild J B, Butt H Z, Choke E, Sayers R D, Bown M J
Abstract excerpt
BACKGROUND: MicroRNAs are crucial in the regulation of cardiovascular disease and represent potential therapeutic targets to decrease abdominal aortic aneurysm (AAA) expansion. The aim of this study was to identify circulating microRNAs associated with AAA. METHODS: Some 754 microRNAs in whole-blood samples from 15 men with an AAA and ten control subjects were quantified using quantitative reverse...
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