Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Vitamin D3 alters macrophage phenotype and endosomal trafficking markers in dairy cattle naturally infected with Mycobacterium avium subsp. paratuberculosis.

Frontiers in cellular and infection microbiology - 1 Jan 2022

Wherry Taylor L T, Dassanayake Rohana P, Bannantine John P, Mooyottu Shankumar, Stabel Judith R

Abstract excerpt

Macrophages are important host defense cells in ruminant paratuberculosis (Johne's Disease; JD), a chronic enteritis caused by Mycobacterium avium subsp. paratuberculosis (MAP). Classical macrophage functions of pathogen trafficking, degradation, and antigen presentation are interrupted in mycobacterial infection. Immunologic stimulation by 25-hydroxyvitamin D3 (25(OH)D3) and 1,25-dihydroxyvitamin D3...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cattle
Share to Cattle Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cholecalciferol

Share to Macrophages

Share to Mycobacterium avium subsp. paratuberculosis

Share to Paratuberculosis

Share to Phenotype

Share to rab GTP-Binding Proteins

Source

Open in PubMed Open full text

Identifiers

PMID: 36275033
DOI: 10.3389/fcimb.2022.1021657
PMCID: PMC9579537

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Vitamin D3 alters macrophage phenotype and endosomal trafficking markers in dairy cattle naturally infected with Mycobacterium avium subsp. paratuberculosis.PMID 36275033Read ↗

Stage of infection with Mycobacterium avium subsp. paratuberculosis impacts expression of Rab5, Rab7, and CYP27B1 in macrophages within the ileum of naturally infected cowsSemantic proximity Read ↗

Transcriptome Profiling of Bovine Macrophages Infected by Mycobacterium avium spp. paratuberculosis Depicts Foam Cell and Innate Immune Tolerance Phenotypes.Semantic proximity Read ↗

Phenotypes of macrophages present in the intestine are impacted by stage of disease in cattle naturally infected with Mycobacterium avium subsp. paratuberculosisSemantic proximity Read ↗

From mouth to macrophage: mechanisms of innate immune subversion by Mycobacterium avium subsp. paratuberculosisSemantic proximity Read ↗

Analysis of the Bovine Monocyte-Derived Macrophage Response to Mycobacterium avium Subspecies Paratuberculosis Infection Using RNA-seqSemantic proximity Read ↗

Prediction of Johne’s disease state based on quantification of T cell markers and their interaction with macrophages in the bovine intestineSemantic proximity Read ↗

Macrophage polarization in cattle experimentally exposed toMycobacterium aviumsubsp.paratuberculosisSemantic proximity Read ↗

Anti-Inflammatory and Antiapoptotic Responses to Infection: A Common Denominator of Human and Bovine Macrophages Infected with<i>Mycobacterium avium</i>Subsp.<i>paratuberculosis</i>Semantic proximity Read ↗

Transcriptional Profiling of Ileocecal Valve of Holstein Dairy Cows Infected with Mycobacterium avium subsp. ParatuberculosisSemantic proximity Read ↗

T and B cell activation profiles from cows with and without Johne's disease in response to in vitro stimulation with Mycobacterium avium subspecies paratuberculosis.Semantic proximity Read ↗

Gene expression profiles during subclinical Mycobacterium avium subspecies paratuberculosis infection in sheep can predict disease outcomeSemantic proximity Read ↗

The role of IL-10 in Mycobacterium avium subsp. paratuberculosis infectionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.