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Article

Practical Considerations for the Use of Circulating Tumor DNA in the Treatment of Patients With Cancer: A Narrative Review.

JAMA oncology - 1 Dec 2022

Krebs Matthew G, Malapelle Umberto, André Fabrice, Paz-Ares Luis, Schuler Martin, Thomas David M, Vainer Gilad, Yoshino Takayuki, Rolfo Christian

Abstract excerpt

Importance: Personalized medicine based on tumor profiling and identification of actionable genomic alterations is pivotal in cancer management. Although tissue biopsy is still preferred for diagnosis, liquid biopsy of blood-based tumor analytes, such as circulating tumor DNA, is a rapidly emerging technology for tumor profiling. Observations: This review presents a practical overview for clinicians and allied...

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Identifiers

PMID: 36264554
DOI: 10.1001/jamaoncol.2022.4457

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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