Article
Liquid biopsy and its role in an advanced clinical trial for lung cancer.
Experimental biology and medicine (Maywood, N.J.) - 1 Feb 2018
Johann Donald J, Steliga Mathew, Shin Ik J, Yoon Donghoon, Arnaoutakis Konstantinos, Hutchins Laura, Liu Meeiyueh, Liem Jason, Walker Karl, Pereira Andy, Yang Mary, Jeffus Susanne K, Peterson Erich, Xu Joshua
Abstract excerpt
Liquid biopsy methodologies, for the purpose of plasma genotyping of cell-free DNA (cfDNA) of solid tumors, are a new class of novel molecular assays. Such assays are rapidly entering the clinical sphere of research-based monitoring in translational oncology, especially for thoracic malignancies. Potential applications for these blood-based cfDNA assays include: (i) initial diagnosis, (ii) response to therapy and...
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