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The Inflammation Biomarker GlycA Reflects Plasma N-Glycan Branching

18 Oct 2022

Abstract excerpt

BACKGROUND: GlycA is a nuclear magnetic resonance (NMR) signal in plasma that correlates with inflammation and cardiovascular outcomes in large data sets. The signal is thought to originate from N-acetylglucosamine (GlcNAc) residues of branched plasma N-glycans, though direct experimental evidence is limited. Trace element concentrations affect plasma glycosylation patterns and may thereby also influence GlycA....

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PMID: 36254612
DOI: 10.1093/clinchem/hvac160

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