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N-Glycosylation Profiles of Immunoglobulin G and Future Cardiovascular Events

13 Feb 2024

Abstract excerpt

BACKGROUND: Posttranslational glycosylation of IgG can modulate its inflammatory capacity through structural variations. We examined the association of baseline IgG N-glycans and an IgG glycan score with incident cardiovascular disease (CVD). METHODS: IgG N-glycans were measured in 2 nested CVD case-control studies: JUPITER (Justification for the Use of Statins in Prevention: an Intervention Trial Evaluating...

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PMID: 38348651
DOI: 10.1161/circresaha.123.323623

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