Article
Genetic Variants of VDR and PGC-1α Are Not Associated with the Risk of Endometriosis in Indian Women.
DNA and cell biology - 1 Nov 2022
Beeram Himabindu, Siddamalla Swapna, Tumu Venkat Reddy, Kv Veena, Vidala Akanksha, Deenadayal Mamata, Sisinthy Shivaji, Bhanoori Manjula
Abstract excerpt
An aberrant immunologic mechanism and mitochondrial biogenesis have been suggested to be involved in the pathogenesis of endometriosis. Genetic alterations in the vitamin D receptor (VDR) gene and peroxisome proliferator-activated receptor-gamma coactivator 1α (PGC-1α) may lead to important defects in gene activation, which principally affect immune function and normal mitochondrial function. Therefore, we...
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