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Metaphase II oocytes from human unilaminar follicles grown in a multi-step culture system

26 Jan 2018

Abstract excerpt

STUDY QUESTION: Can complete oocyte development be achieved from human ovarian tissue containing primordial/unilaminar follicles and grown in vitro in a multi-step culture to meiotic maturation demonstrated by the formation of polar bodies and a Metaphase II spindle? SUMMARY ANSWER: Development of human oocytes from primordial/unilaminar stages to resumption of meiosis (Metaphase II) and emission of a polar body...

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PMID: 29390119
DOI: 10.1093/molehr/gay002

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