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Article

Phenotypic and functional characterisation of synovial fluid-derived neutrophils in knee osteoarthritis and knee infection.

Osteoarthritis and cartilage - 1 Jan 2023

Manukyan G, Gallo J, Mikulkova Z, Trajerova M, Savara J, Slobodova Z, Fidler E, Shrestha B, Kriegova E

Abstract excerpt

OBJECTIVE: An increase in the number of neutrophils (NEUs) has long been associated with infections in the knee joints; however, their impact on knee osteoarthritis (KOA) pathophysiology remains largely unexplored. DESIGN: This study compared the phenotypic and functional characteristics of synovial fluid (SF)-derived NEUs in KOA and knee infection (INF). RESULTS: KOA NEUs were characterised by a lower expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36216277
DOI: 10.1016/j.joca.2022.09.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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