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Article

SARS-CoV-2 RNA-dependent RNA polymerase as a therapeutic target for COVID-19

21 Jan 2021

Abstract excerpt

Introduction: The current SARS-CoV-2 pandemic urgently demands for both prevention and treatment strategies. RNA-dependent RNA-polymerase (RdRp), which has no counterpart in human cells, is an excellent target for drug development. Given the time-consuming process of drug development, repurposing drugs approved for other indications or at least successfully tested in terms of safety and tolerability, is an...

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PMID: 33475441
DOI: 10.1080/13543776.2021.1880568

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