Article
Role of genetic variations of DNA damage response pathway genes and heat-shock proteins in increased head and neck cancer risk.
Future oncology (London, England) - 1 Oct 2022
Mahjabeen Ishrat, Sheshe Sadeeq, Shakoor Tehmina, Hussain Muhammad Zahid, Rizwan Muhammad, Mehmood Azher, Haris Muhammad Shahbaz, Fazal Falak, Burki Ayesha, Kayani Mahmood Akhtar
Abstract excerpt
Aim: The present study was designed to evaluate the role of DNA damage response pathway genes and heat-shock proteins in head and neck cancer (HNC) risk. Methods: For this purpose, two study cohorts were used. Cohort 1 (blood samples of 250 HNC patients and 250 controls) was used for polymorphism screening of selected genes using tetra-primer amplification refractory mutation system-polymerase chain (Tetra-ARMS...
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