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Aldehyde dehydrogenase 2 polymorphism is associated with chemotherapy-related cognitive impairment in patients with breast cancer who receive chemotherapy.

Cancer medicine - 1 Mar 2023

Yao Senbang, Li Wen, Liu Shaochun, Cai Yinlian, Zhang Qianqian, Tang Lingxue, Yu Sheng, Jing Yanyan, Yin Xiangxiang, Cheng Huaidong

Abstract excerpt

BACKGROUND: Chemotherapy-related cognitive impairment (CRCI) is a common but easily overlooked condition that markedly affects the quality of life (QOL) of patients with breast cancer. The rs671 is a common gene polymorphism of aldehyde dehydrogenase 2 (ALDH2) in Asia that is involved in aldehyde metabolism and may be closely related to CRCI. However, no study has yet summarised the association between ALDH2 and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36200595
DOI: 10.1002/cam4.5319
PMCID: PMC10028021

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