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Article

Relationship between alcohol metabolism and chemotherapy-induced emetic events in breast cancer patients.

Breast cancer (Tokyo, Japan) - 1 Sept 2017

Uomori Toshitaka, Horimoto Yoshiya, Mogushi Kaoru, Matsuoka Joe, Saito Mitsue

Abstract excerpt

BACKGROUND: Chemotherapy-induced nausea and vomiting (CINV) can negatively affect quality of life and treatment compliance in breast cancer patients. Habitual alcohol consumption reportedly shows an inverse correlation with CINV, though the underlying mechanism is unknown. Acetaldehyde dehydrogenase 2 (ALDH2), one of the two ALDH isozymes, is reportedly the major factor among several genetic polymorphisms...

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Identifiers

PMID: 28217830
DOI: 10.1007/s12282-017-0761-4

Genes

ALDH2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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