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Article

Genetic variation in genes of inborn errors of immunity in children with unexplained encephalitis.

Genes and immunity - 1 Nov 2022

Malik Devesh, Simon Dennis W, Thakkar Kavita, Rajan Deepa S, Kernan Kate F

Abstract excerpt

Pediatric encephalitis has significant morbidity and mortality, yet 50% of cases are unexplained. Host genetics plays a role in encephalitis' development; however, the contributing variants are poorly understood. One child with anti-NMDA receptor encephalitis and ten with unexplained encephalitis underwent whole genome sequencing to identify rare candidate variants in genes known to cause monogenic immunologic...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 36198812
DOI: 10.1038/s41435-022-00185-5
PMCID: PMC9533258

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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