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Impact of antigen test target failure and testing strategies on the transmission of SARS-CoV-2 variants

5 Oct 2022

Abstract excerpt

Population testing remains central to COVID-19 control and surveillance, with countries increasingly using antigen tests rather than molecular tests. Here we describe a SARS-CoV-2 variant that escapes N antigen tests due to multiple disruptive amino-acid substitutions in the N protein. By fitting a multistrain compartmental model to genomic and epidemiological data, we show that widespread antigen testing in the...

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Share to Advanced biosensing and bioanalysis techniques
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PMID: 36198689
DOI: 10.1038/s41467-022-33460-0

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