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Population impact of SARS-CoV-2 variants with enhanced transmissibility and/or partial immune escape

19 Nov 2021

Abstract excerpt

SARS-CoV-2 variants of concern exhibit varying degrees of transmissibility and, in some cases, escape from acquired immunity. Much effort has been devoted to measuring these phenotypes, but understanding their impact on the course of the pandemic-especially that of immune escape-has remained a challenge. Here, we use a mathematical model to simulate the dynamics of wild-type and variant strains of SARS-CoV-2 in...

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PMID: 34910927
DOI: 10.1016/j.cell.2021.11.026

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