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The application of genome-wide CRISPR-Cas9 screens to dissect the molecular mechanisms of toxins

1 Jan 2022

Abstract excerpt

Many toxins are life-threatening to both animals and humans. However, specific antidotes are not available for most of those toxins. The molecular mechanisms underlying the toxicology of well-known toxins are not yet fully characterized. Recently, the advance in CRISPR-Cas9 technologies has greatly accelerated the process of revealing the toxic mechanisms of some common toxins on hosts from a genome-wide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 36187925
DOI: 10.1016/j.csbj.2022.09.012

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