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Genome-wide CRISPR screens and their applications in infectious disease

19 Sept 2023

Abstract excerpt

Inactivation or targeted disruption of a gene provides clues to assess the function of the gene in many cellular processes. Knockdown or knocking out a gene has been widely used for this purpose. However, recently CRISPR mediated genome editing has taken over the knockout/knockdown system with more precision. CRISPR technique has enabled us to perform targeted mutagenesis or genome editing to address questions in...

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PMID: 37794981
DOI: 10.3389/fgeed.2023.1243731

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