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Article

Establishment and application of a CRISPR-Cas12a-based RPA-LFS and fluorescence for the detection of Trichomonas vaginalis

30 Sept 2022

Abstract excerpt

BACKGROUND: Infection with Trichomonas vaginalis can lead to cervicitis, urethritis, pelvic inflammatory disease, prostatitis and perinatal complications and increased risk of HIV transmission. Here, we used an RPA-based CRISPR-Cas12a assay system in combination with a lateral flow strip (LFS) (referred to as RPA-CRISPR-Cas12a) to establish a highly sensitive and field-ready assay and evaluated its ability to...

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PMID: 36180879
DOI: 10.1186/s13071-022-05475-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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