Article
Patients with severe coronavirus disease 2019 have high frequency of factor 5 Leiden and prothrombin gene mutations.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Jan 2023
Avci Burcu Altindağ, Doğan Mustafa, Batar Bahadir, Yildirim İlker, Serdal Elif, Gezer Sümbül, Onar Çağatay L, Akpinar Seval, Turgut Burhan
Abstract excerpt
We investigated the frequency of factor 5 Leiden (FVL) and prothrombin gene (PTG) mutations in patients with severe coronavirus disease 2019 (COVID-19). Our primary aim is to reveal whether these mutations are associated with severity of disease and mortality. A total of 249 patients were included in this cross-sectional study. Severe COVID-19 cases (with oxygen saturation of less than 90 mmHg and who received...
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