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Comparative single-cell transcriptomes of dose and time dependent epithelial–mesenchymal spectrums

9 Jul 2022

Abstract excerpt

Abstract Epithelial–mesenchymal transition (EMT) is a cellular process involved in development and disease progression. Intermediate EMT states were observed in tumors and fibrotic tissues, but previous in vitro studies focused on time-dependent responses with single doses of signals; it was unclear whether single-cell transcriptomes support stable intermediates observed in diseases. Here, we performed...

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PMID: 36159174
DOI: 10.1093/nargab/lqac072

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