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Article

Rational development of combination therapies for biliary tract cancers.

Journal of hepatology - 1 Jan 2023

Harding James J, Khalil Danny N, Fabris Luca, Abou-Alfa Ghassan K

Abstract excerpt

Biliary tract cancers are an uncommon set of gastrointestinal malignancies that are associated with high morbidity and mortality rates. Most patients present with incurable locally advanced or metastatic disease. The pathophysiology of biliary tract cancer can be exploited for direct therapeutic benefit, and indeed, chemotherapy, precision medicine, immunotherapy and combination treatments are now applied as both...

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Identifiers

PMID: 36150578
DOI: 10.1016/j.jhep.2022.09.004
PMCID: PMC11111174

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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