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New Statement about NRF2 in Amyotrophic Lateral Sclerosis and Frontotemporal Dementia

29 Aug 2022

Abstract excerpt

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are related neurodegenerative disorders displaying substantial overlay, although there are substantial differences at the molecular level. Currently, there is no effective treatment for these diseases. The transcription factor NRF2 has been postulated as a promising therapeutic target as it is capable of modulating key pathogenic events...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 36139039
DOI: 10.3390/biom12091200

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