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Article

Accurate prediction of virus-host protein-protein interactions via a Siamese neural network using deep protein sequence embeddings

31 Jul 2022

Abstract excerpt

Prediction and understanding of virus-host protein-protein interactions (PPIs) have relevance for the development of novel therapeutic interventions. In addition, virus-like particles open novel opportunities to deliver therapeutics to targeted cell types and tissues. Given our incomplete knowledge of PPIs on the one hand and the cost and time associated with experimental procedures on the other, we here propose...

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PMID: 36124304
DOI: 10.1016/j.patter.2022.100551

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