Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bilateral Ovarian Sertoli-Leydig Cell Tumors Harboring DICER1 Germline and Distinct Somatic Mutations: Case Report and Literature Review.

Fetal and pediatric pathology - 1 Jun 2023

Hughes Caitlin E, Liang Jiancong, Paulson Vera, Wang Huiying

Abstract excerpt

Background: DICER1 tumor predisposition syndrome is characterized by an increased risk for development of pleuropulmonary blastoma, pituitary blastoma, multinodular thyroid goiter, thyroid carcinoma, sex cord stromal tumor, cystic nephroma, embryonal rhabdomyosarcoma, and tumors of the CNS, amongst others. Of this list, only pituitary blastoma is recognized as pathognomonic for the syndrome. Case report: We...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adolescent
Share to DEAD-box RNA Helicases

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mutation

Share to Ovarian Neoplasms

Share to Ribonuclease III

Source

Identifiers

PMID: 36121434
DOI: 10.1080/15513815.2022.2120787

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bilateral Ovarian Sertoli-Leydig Cell Tumors Harboring DICER1 Germline and Distinct Somatic Mutations: Case Report and Literature Review.PMID 36121434Read ↗

Somatic tumour testing establishes that bilateral DICER1-associated ovarian Sertoli-Leydig cell tumours represent independent primary neoplasms.Semantic proximity Read ↗

Ovarian tumors related to intronic mutations in DICER1: a report from the international ovarian and testicular stromal tumor registry.Semantic proximity Read ↗

DICER1-Pleuropulmonary Blastoma Familial Tumor Predisposition SyndromeSemantic proximity Read ↗

DICER1 Mutations and Differentiated Thyroid Carcinoma: Evidence of a Direct Association.Semantic proximity Read ↗

Primary Biphasic Hepatic Sarcoma in DICER1 Syndrome.Semantic proximity Read ↗

Pleuropulmonary blastoma-like peritoneal sarcoma: a newly described malignancy associated with biallelic DICER1 pathogenic variation.Semantic proximity Read ↗

DICER1-related Sertoli-Leydig cell tumor and gynandroblastoma: Clinical and genetic findings from the International Ovarian and Testicular Stromal Tumor Registry.Semantic proximity Read ↗

The co-occurrence of an ovarian Sertoli-Leydig cell tumor with a thyroid carcinoma is highly suggestive of a DICER1 syndrome.Semantic proximity Read ↗

DICER1 syndrome: clarifying the diagnosis, clinical features and management implications of a pleiotropic tumour predisposition syndrome.Semantic proximity Read ↗

The Histological Spectrum of DICER1-Associated Neoplasms.Semantic proximity Read ↗

Prognostic Significance of Germline DICER1 Pathogenic or Likely Pathogenic Variants in Outcomes of Ovarian Sertoli-Leydig Cell TumorSemantic proximity Read ↗

Pediatric imaging in DICER1 syndrome.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.