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Article

Drug resistance in idiopathic generalized epilepsies: Evidence and concepts

14 Sept 2022

Abstract excerpt

Although approximately 10%-15% of patients with idiopathic generalized epilepsy (IGE)/genetic generalized epilepsy remain drug-resistant, there is no consensus or established concept regarding the underlying mechanisms and prevalence. This review summarizes the recent data and the current hypotheses on mechanisms that may contribute to drug-resistant IGE. A literature search was conducted in PubMed and Embase for...

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PMID: 36102351
DOI: 10.1111/epi.17410

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