Article
Presence of antibodies against HLA class I and class II molecules in children before and after allo-HSCT. Alloantibodies before and after HSCT.
HLA - 1 Jan 2023
Morán-Espinosa Maricarmen, Angeles-Floriano Tania, Parra-Ortega Israel, Gaytán-Morales Félix, Castorena-Villa Iván, López-Martínez Briceida, Ortiz-Navarrete Vianney, Olvera-Gómez Irlanda
Abstract excerpt
A severe complication of allogeneic hematopoietic stem cell transplantation (HSCT) is graft failure (GF). Among others, donor-specific anti-HLA antibodies (DSA) are associated with graft rejection after allogeneic or haploidentical transplantation in adults. Knowledge of DSA and pediatric recipients is limited. Hence, we aimed to generate more information about the presence of DSA (pre- and post-HSCT) and the...
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